Yes, I do that literally every time (21gal custom homemade eBIAB). 2row + 20% rye, 20 ibu noble/spicy hopstand, then add 2lbs of D90/D180 or dextrose as fermentation winds down, and I have a dubbel (or quad) + tripple, depending on strength and dark syrups.
Another split I often do is run-off...