To be clear, I have already made this beer. So I'm just curious if anyone else has used this yeast for an IPA? Either way, I'll report on my experiment. Had the yeast cake from a wit and just got it done.
I think you could consider it a Belgian IPA and yes there would be esters, but I think it would work OK. 400 has a tart flavor (at least with a high percentage of wheat in the grist) that would blend with American hops IMO.
I have a feeling that a lot of "non-standard" yeasts will do very well in an IPA if the brewer understands what comes from said yeast and knows how to make things happen.
Tart can work with an IPA if not too strong. I would be inclined to use a lot of Citra/ElDorado in whirlpool and dry hop. Tartness would be a subtext and should compliment fruity citrus. Just ferment lower and keep phenols in check.
I was definitely careful to keep things cool, or at least not hot when fermenting. Initial impression was good - definitely on the dry side. I generally like a little residual sweetness to balance the hops, but I think this will work out. Used mosaic and lemon drop as dry hops, with some azacca. In bottles now, will update with tasting notes once it's carbonated.
I've used WLP400 for non-witbiers several times. It does produce small amounts of the typical Belgian phenols. Also it produces a pear-like fruity ester. I think it is a great match for an IPA. Go for it.
Just reporting back - end result is super tasty and ages well, as a high alcohol brew. I have to say that I would not hesitate to use 400 in this capacity again.